Isaac Guerendo Props

Isaac Guerendo (RB) of the San Francisco 49ers is going up against The Houston Texans on October 26, 2025 at 1:00 PM ET. They have 34 bets across 6 sportsbooks. Check out the odds below, or view them directly in Gambly chat for the most up-to-date odds.

Opening Lines
Bet All
Isaac Guerendo
HOU @ SF
Oct 26 at 5:00 PM
Isaac Guerendo
Player - First Team Touchdown
+2200
Fanatics
Isaac Guerendo
HOU @ SF
Oct 26 at 5:00 PM
Isaac Guerendo No
First Player To Score Touchdown
+6000
Fanatics
Isaac Guerendo
HOU @ SF
Oct 26 at 5:00 PM
Isaac Guerendo
Second Half Anytime Touchdown Scorer
+3500
DraftKings
Isaac Guerendo
HOU @ SF
Oct 26 at 5:00 PM
Isaac Guerendo
First Quarter Anytime Touchdown Scorer
+7000
DraftKings
I. Guerendo
HOU @ SF
Oct 26 at 5:00 PM
I. Guerendo
Last To Score Touchdown
+9000
DraftKings
Isaac Guerendo
HOU @ SF
Oct 26 at 5:00 PM
Isaac Guerendo
Player to Score in Both Halves
+20000
DraftKings
Isaac Guerendo
HOU @ SF
Oct 26 at 5:00 PM
Isaac Guerendo Under 0.5
Anytime Touchdown Scorer
0.5
+1700
Fanatics
Isaac Guerendo
HOU @ SF
Oct 26 at 5:00 PM
Isaac Guerendo Under 0.5
Anytime Touchdown Scorer
0.5
-13790
Fliff
Isaac Guerendo
HOU @ SF
Oct 26 at 5:00 PM
Isaac Guerendo Under 0.5
Anytime Touchdown Scorer
0.5
+3135
Fliff
Isaac Guerendo
HOU @ SF
Oct 26 at 5:00 PM
Isaac Guerendo Under 0.5
First Quarter Anytime Touchdown Scorer
0.5
+15000
FanDuel
Isaac Guerendo
HOU @ SF
Oct 26 at 5:00 PM
Isaac Guerendo Under 0.5
Second Quarter Anytime Touchdown Scorer
0.5
+10000
FanDuel
Isaac Guerendo
HOU @ SF
Oct 26 at 5:00 PM
Isaac Guerendo
Player to Have 2+ Touchdowns
+40000
FanDuel
Isaac Guerendo
HOU @ SF
Oct 26 at 5:00 PM
Isaac Guerendo Under 0.5
Anytime Touchdown Scorer
0.5
+2400
Novig
Isaac Guerendo
HOU @ SF
Oct 26 at 5:00 PM
Isaac Guerendo Under 0.5
Third Quarter Anytime Touchdown Scorer
0.5
+10000
FanDuel
Isaac Guerendo
HOU @ SF
Oct 26 at 5:00 PM
Isaac Guerendo Under 0.5
Fourth Quarter Anytime Touchdown Scorer
0.5
+10000
FanDuel
Isaac Guerendo
HOU @ SF
Oct 26 at 5:00 PM
Isaac Guerendo Under 0.5
Second Half Anytime Touchdown Scorer
0.5
+5500
FanDuel
Isaac Guerendo
HOU @ SF
Oct 26 at 5:00 PM
Isaac Guerendo Under 0.5
First Half Anytime Touchdown Scorer
0.5
+6500
FanDuel
Isaac Guerendo
HOU @ SF
Oct 26 at 5:00 PM
Isaac Guerendo
Player - First Team Touchdown
+5000
DraftKings
I. Guerendo
HOU @ SF
Oct 26 at 5:00 PM
I. Guerendo
Last To Score Touchdown
+10000
FanDuel
Isaac Guerendo
HOU @ SF
Oct 26 at 5:00 PM
Isaac Guerendo No
First Player To Score Touchdown
+10000
FanDuel
Isaac Guerendo
HOU @ SF
Oct 26 at 5:00 PM
Isaac Guerendo No
Second Half First Player To Score Touchdown
+10000
FanDuel
Isaac Guerendo
HOU @ SF
Oct 26 at 5:00 PM
Isaac Guerendo No
First Player To Score Touchdown
+8991
Novig
Isaac Guerendo
HOU @ SF
Oct 26 at 5:00 PM
Isaac Guerendo Under 0.5
Anytime Touchdown Scorer
0.5
+3000
FanDuel
Isaac Guerendo
HOU @ SF
Oct 26 at 5:00 PM
Isaac Guerendo No
First Player To Score Touchdown
+9500
Caesars
Isaac Guerendo
HOU @ SF
Oct 26 at 5:00 PM
Isaac Guerendo Under 0.5
Anytime Touchdown Scorer
0.5
+2600
Caesars
Isaac Guerendo
HOU @ SF
Oct 26 at 5:00 PM
Isaac Guerendo Under 0.5
Anytime Touchdown Scorer
0.5
+2200
DraftKings
Isaac Guerendo
HOU @ SF
Oct 26 at 5:00 PM
Isaac Guerendo
Player - First Team Touchdown
+7500
FanDuel
Isaac Guerendo
HOU @ SF
Oct 26 at 5:00 PM
Isaac Guerendo
Player to Have 3+ Touchdowns
+40000
FanDuel
Isaac Guerendo
HOU @ SF
Oct 26 at 5:00 PM
Isaac Guerendo
Player to Have 2+ Touchdowns
+20000
DraftKings
Isaac Guerendo
HOU @ SF
Oct 26 at 5:00 PM
Isaac Guerendo No
Second Half First Player To Score Touchdown
+8000
DraftKings
Isaac Guerendo
HOU @ SF
Oct 26 at 5:00 PM
Isaac Guerendo No
First Player To Score Touchdown
+8000
DraftKings
Isaac Guerendo
HOU @ SF
Oct 26 at 5:00 PM
Isaac Guerendo
First Half Anytime Touchdown Scorer
+4500
DraftKings
I. Guerendo
HOU @ SF
Oct 26 at 5:00 PM
I. Guerendo
Last To Score Touchdown
+7000
Fanatics
Isaac Guerendo
HOU @ SF
Oct 26 at 5:00 PM
Isaac Guerendo
Player to Have 2+ Touchdowns
+18000
Fanatics

The Best Books To Bet Isaac Guerendo Props

  • Player - First Team Touchdown: The best book to bet Player - First Team Touchdown is FanDuel, which offers Isaac Guerendo +7500.
  • First Player To Score Touchdown: The best book to bet First Player To Score Touchdown is FanDuel, which offers Isaac Guerendo +10000.
  • Anytime Touchdown Scorer: The best book to bet Anytime Touchdown Scorer is FanDuel, which offers Isaac Guerendo (O 0.5) at +15000.
  • Last To Score Touchdown: The best book to bet Last To Score Touchdown is FanDuel, which offers Isaac Guerendo +10000.
  • Player to Score in Both Halves: The best book to bet Player to Score in Both Halves is DraftKings, which offers Isaac Guerendo +20000.
  • Player to Have 2+ Touchdowns: The best book to bet Player to Have 2+ Touchdowns is FanDuel, which offers Isaac Guerendo +40000.
  • Player to Have 3+ Touchdowns: The best book to bet Player to Have 3+ Touchdowns is FanDuel, which offers Isaac Guerendo +40000.

Line Shopping & Betting Tips

Maximizing your potential returns starts with finding the best lines across multiple sportsbooks. Even a small shift in odds can lead to better payouts, so it pays to compare. Always keep an eye on Murray's listed props - you never know when a book might offer more favorable odds.