Derwin James Props

Derwin James (SAF) of the Los Angeles Chargers is going up against The Denver Broncos on September 21, 2025 at 4:05 PM ET. They have 48 bets across 11 sportsbooks. Check out the odds below, or view them directly in Gambly chat for the most up-to-date odds.

Opening Lines

Bet All

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

Player Tackles

3.5

+105

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

Tackles and Assists

6.5

-111

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

ALT

0.25

-10000

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

Tackles and Assists

6.5

-170

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

Tackles and Assists

6.5

+110

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

Player Tackles

3.5

-181

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

ALT

4.5

+135

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

Defensive Player Anytime TD

+5500

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

Sacks

0.5

+495

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

Anytime Touchdown Scorer

0.5

-999905

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

Sacks

0.5

-1380

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

Anytime Touchdown Scorer

0.5

+1595

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

Defensive Interceptions

0.5

-1515

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

Defensive Interceptions

0.5

+515

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

Player Tackles

3.5

-189

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

Tackles and Assists

6.5

-155

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

Sacks

0.5

+510

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

Tackles and Assists

5.5

-162

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

Player To Record A Sack

+550

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

Sacks

0.25

+488

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

Tackles and Assists

6.5

-110

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

Tackles and Assists

6.5

-118

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

Sacks

0.25

-690

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

Player Tackles

3.5

+111

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

Tackles and Assists

6.5

-135

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

Sacks

0.5

-833

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

Sacks

0.5

+484

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

Defensive Interceptions

0.5

-1667

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

Sacks

0.5

+575

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

Anytime Touchdown Scorer

+5000

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

Tackles and Assists

6.5

+120

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

Defensive Interceptions

0.5

-1667

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

Sacks

0.5

+484

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

Sacks

0.5

-833

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

Player Tackles

3.5

+105

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

Defensive Interceptions

0.5

+539

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

ALT

6.5

+115

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

Player Tackles

3.5

-165

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

Player To Record An Interception

+600

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

Tackles and Assists

-118

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

Tackles and Assists

-118

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

Tackles and Assists

6.5

-155

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

Sacks

0.5

-1000

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

Anytime Touchdown Scorer

-9000

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

Defensive Interceptions

0.5

+729

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

Defensive Interceptions

0.5

+729

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

ALT

0.5

+559

Sun, Sep 21, 8:05 PM

Los Angeles Chargers @ Denver Broncos

Derwin James

Tackles and Assists

6.5

-122

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The Best Books To Bet Derwin James Props

Player Tackles: The best book to bet Player Tackles is Fanatics, which offers Derwin James (O 4.5) at +135.
Tackles and Assists: The best book to bet Tackles and Assists is Hard Rock, which offers Derwin James (O 6.5) at +120.
Sacks: The best book to bet Sacks is Hard Rock, which offers Derwin James (O 0.5) at +575.
Defensive Player Anytime TD: The best book to bet Defensive Player Anytime TD is FanDuel, which offers Derwin James +5500.
Anytime Touchdown Scorer: The best book to bet Anytime Touchdown Scorer is Hard Rock, which offers Derwin James +5000.
Defensive Interceptions: The best book to bet Defensive Interceptions is BetOnline, which offers Derwin James (O 0.5) at +729.
Player To Record A Sack: The best book to bet Player To Record A Sack is FanDuel, which offers Derwin James +550.
Player To Record An Interception: The best book to bet Player To Record An Interception is BetRivers, which offers Derwin James (O 1.0) at +600.

Line Shopping & Betting Tips

Maximizing your potential returns starts with finding the best lines across multiple sportsbooks. Even a small shift in odds can lead to better payouts, so it pays to compare. Always keep an eye on Murray's listed props - you never know when a book might offer more favorable odds.